A recent study from Cell Reports Medicine reports that a single dose of the Sputnik V vaccine could elicit a significant antibody response against SARS-CoV-2, especially in previously infected people. Massive immunization holds potential in terms of controlling the global COVID-19 epidemic . However, amid limited vaccine availability and uneven vaccine distribution, it is important to optimize the vaccination strategy. Sputnik V (Gam-COVID-Vac) is a combined vector vaccine made up of recombinant adenovirus (rAd) types 26 and 5.
Researchers examined the effects of one and two Sputnik V shots on SARS-CoV-2-specific antibody responses (n=227) and virus-neutralizing antibodies (n=62) in 289 healthcare workers in Argentina. Plasma samples were obtained before vaccination (baseline), 21 days after the first dose, and 21 days after the second dose. Results After the first dose, 94% of…
