Steven Johnson Syndrome is a uveocutaneous syndrome. Epidemiology incidence 2 to 7 cases per million. Women are more affected than men occurrence ratio 2:1.
Highly associated with certain medication like sulphas and some injections. Symptoms Prodromal phase with high fever, sore throat malaise, widespread erythematous rash, tenderness. Signs Mucocutaneous ulcers and maculae with progression to vesicles and bullae Severe membranous conjunctivitis corneal epithelial defects treatment iv Ig and supportive Treatment Topical steroids and antibiotics Consider amniotic membrane transplantation acutely for moderate to severe cases Chronic sequelae may be treated with Boston keratoprosthesis Keratolimbal allografting Share your views.
