Short-term use of benzodiazepines (BZD) is recommended as they can lead to tolerance, dependence (addiction) and abuse. Potent benzodiazepines with shorter elimination half-lives (triazolam, alprazolam, lorazepam) may be the most prone to causing problems with tolerance and dependence. If the drug is stopped suddenly, especially those that are shorter-acting, withdrawal reactions can also occur.
Sudden discontinuation can also lead to rebound insomnia, making sleep difficult, and perpetuating continued use and higher doses of benzodiazepines. Thus, what strategies would you suggest for discontinuing BZD therapy to avoid its withdrawal reactions?
