Subclinical hypothyroidism (SCH), defined by persistently elevated TSH with normal FT4 levels, is the most commonly diagnosed thyroid disorder in the Indian population. Despite its prevalence, clinical recognition is challenging due to nonspecific or absent symptoms. The recently updated Indian Thyroid Society guidelines provide a refined approach to SCH diagnosis, risk stratification, and treatment, incorporating the latest global and Indian evidence.
These recommendations emphasize age-specific thresholds, comorbidities, and individualized therapy, particularly focusing on when to initiate levothyroxine. A graded evidence-based methodology was applied to formulate the recommendations, aiming to optimize decision-making for adult SCH management. Special populations, such as the elderly or those with cardiovascular disease, receive particular attention due to differing treatment…
