It has been reported that travel in a way that misaligns their internal 24-hour clock with the natural environment and its cycle of sunlight, they suffer negative consequences. A modest trip across two or three time zones can have ‘detectable and significant’ effects. The negative effects of jet lag are found to be subtle, but they are detectable and significant.

It is argued, that the effect is due to the circadian clock, and not the travel itself. How to deal with jet lag and reduce the gravity of its damage that potentially impact the performance of an individual?