The use of folic acid in the early and late pregnancy may have different outcomes. While in the early pregnancy (1 st trimester) maternal consumption of folic acid helps in the neural tube and CNS development of the growing fetus, the same molecule increases the risk of allergy in the offspring affected by IUGR if taken or continued at late pregnancy (3 rd trimester). IUGR or intrauterine growth restriction causes the low birth weight of the offspring that predominantly result from the smaller-than-normal placenta in the mother.
Previous studies rather showed that IUGR, in fact, protects newborns from allergic reactions. However, the new research provided a prominent link of allergic reaction in the newborns affected by IUGR if the folic acid supplementation continues even in the late pregnancy. The research suggests that late pregnancy folic acid supplementation significantly reduced…
