Kidneys play a crucial role in regulating the composition and volume of body fluids and excreting nitrogenous waste products. Retention of nitrogen wastes results in the disturbance of fluid, electrolyte, and acid-base balance. Dietary modifications can minimize such changes and play an important role in managing patients with chronic kidney disease (CKD). There have been substantial changes in the use of dietary protection restriction (DPR) for the treatment of patients with chronic renal disease (CKD) in the past 5 to 6 decades.
DPR was used widely in uremic patients before the availability of renal replacement therapy (RRT) to reduce the production of nitrogenous waste products and alleviate uremic symptoms. With the introduction of RRT, and the importance of DPR in the management of CKD patients has waned. However, animal experimental studies suggesting that DPR could slow CKD…
