Opoids obtained from resin of poppy or opium bulbs, natural opoids are morphine, codeine and thebaine, but opoids can be synthesized as semisnthetic and synthetic opoids. Semi-synthetic opoids obtained from natural opium bulbs, these are hydrocodone, oxycodone, desmomorphine, heroin or diacetyl morphine, nicomorphine, and benzl/ethl morphine.
Synthetic opioids are manufactured in lab, these are pathidine, tramadol, methadone, fentanyl and dextropropoxyphen Tramadol is a synthetic opioid, centrally acting analgesic, used for moderate to moderately severe pain including post operative pain.in contrast to other opioids it has no clinical relevant effect on respiratory and cardiovascular parameters, its proved useful in patients with poor cardio-pulmonary status, elderly, obese and smoker patients.and works by inhibing opoid mu receotors and ascending pathways of pain. Indications: Chronic…
