Gastro-oesophageal reflux and heartburn are reported by 45 to 85% of women during pregnancy. Typically, the heartburn of pregnancy is new onset and is precipitated by the hormonal effects of estrogen and progesterone on lower oesophageal sphincter function.
Treating the GERD in pregnant women poses a problem for physicians as medications used for treating gastro-oesophageal reflux are not routinely or vigorously tested in randomized controlled trials in women who are pregnant because of ethical and medico-legal concerns What are the safe therapeutic options to treat GERD in pregnant women?
