A 59-year-old man having a history of melanoma (3 years ago) presented to the dermatology clinic for routine check-up. Examination He had macrocephaly (head circumference in the >97 th percentile), as well as multiple trichilemmomas on the face and chest and acral keratosis on the hands and feet. He was also noted to have lingual papillomas, which he recalled had been present for many years. History The patient had a history of hyperplastic and adenomatous gastrointestinal polyps and a multinodular goiter.
Members of his family also had a history of gastrointestinal polyps, thyroid nodules, and macrocephaly. What is the most likely diagnosis? *This case is from Docplexus Editorial Team for educative purpose only Source: NEJM The answer is posted in the comment section. click here.
