In a prospective cohort from the LPS Institute of Cardiology, Kanpur, researchers evaluated transcatheter closure (TCC) of patent ductus arteriosus (PDA) guided solely by anatomo-haemodynamic landmarks, eliminating the need for arteriography or arterial access. Among 250 patients (mean age: 2.3 years; duct size: 6.7 mm), antegrade-only TCC achieved a 99.6% procedural success rate with minimal complications. Immediate closure was observed in 93.2%, and complete closure occurred within 48 hours in the remainder.
Notably, device embolization occurred in only 0.4%, and flow acceleration in the descending thoracic aorta was rare (2%). The study reinforces that a no-artery, landmark-based strategy can deliver safe, efficient, and reproducible outcomes, potentially redefining pediatric PDA intervention protocols. Discover how eliminating arterial access could streamline your next PDA…
