Afamin, the vitamin-E binding glycoprotein has recently been found to be associated with type 2 diabetes mellitus (T2DM), prediabetes, and insulin resistance. The researchers now have confirmed that plasma concentration of afamin can be measured to assess the risk of diabetes. T2DM and prediabetic conditions are largely involved in comorbidities like cardiovascular diseases. Hence, the detection of early risk factors has major significance. In recent studies, afamin has been found to effective to serve this purpose. Afamin is predominantly expressed in the liver.
The recent study analyzed the data from 8 cohort trials with a pool of 20,136 patients. Afamin concentration was measured with “double-antibody Sandwich ELISA ”. The focus was to study the prevalent and incident cases of T2DM, Prediabetes and insulin resistance. The average afamin among studies varied between 61-73 mg/L. It was…
