In 1838, when Johannes Müller first described Cholesteatoma, he thought that it was a tumour of the fatty tissue, (Latin: steat=fat). The reported annual incidence of Cholesteatoma worldwide is around 10 per 100,000. There have been reports of association between cholesteatoma and pediatric progressive sensorineural hearing loss.
Cholesteatoma ears show reduced microbial diversity with predominance gram positive cocci Staphylococcus aureus. Staph aureus cocci are associated with a progressive form of Cholesteatoma.
