Jaundice in pregnancy is uncommon but carries significant maternal and fetal risk, with acute fatty liver of pregnancy (AFLP) representing a life-threatening etiology. We report a case of a 28-year-old primigravida at 35 weeks gestation presenting with severe nausea, vomiting, pedal edema, icterus, and deranged hepatic and renal function tests. Differential diagnoses including viral hepatitis, HELLP syndrome, and intrahepatic cholestasis of pregnancy were systematically excluded.
Using S wansea criteria, the patient met 8 of 14 features indicative of AFLP, including hyperbilirubinemia, hyperuricemia, leukocytosis, elevated transaminases, hyperammonemia, hepatic steatosis on ultrasound, vomiting, and coagulopathy. She underwent an emergency lower segment cesarean section , received targeted transfusion support, and was managed conservatively post-partum. Maternal recovery was favorable,…
