Acute kidney injury (AKI) increases the risk of toxic effects from systemic chemotherapy, jeopardizes the continuation of cancer therapy, and limits patient participation in possibly life-saving clinical trials. Sepsis, metabolic disturbances, the nephrotoxic effects of anticancer therapies, or hematopoietic stem-cell transplantation are few risk factors for acute kidney injury in cancer. Acute kidney injury in patients with cancer is associated with substantial morbidity and mortality.
Risk Factors for Acute Kidney Injury: Sepsis, direct kidney injury due to the primary cancer, metabolic disturbances, the nephrotoxic effects of anticancer therapies, or hematopoietic stem-cell transplantation are few risk factors for acute kidney injury in cancer. Older age (>65 years), female sex, and coexisting disease processes, including chronic kidney disease, diabetic kidney disease, and volume…
