Albinism is genetically determined a heterogeneous group of disorders of melanin. Ocular albinism of the eyes, skin, hair oculocutaneous albinism is affected.
Oculocutaneous albinism can be Tyrosinase-negative Tyrosinase-positive in tyrosinase negative Type ocular features are VA 6 60 due to foveal hypoplasia Nystagmus can be pendular or horizontal Iris is diphorous and translucent Fundus lacks pigment Optic chiasma has fewer uncrossed fibers In tyrosinase-positive albinism, the ocular features are VA is impaired due to foveal hypoplasia Iris may be blue or dark brown with variable translucency Fundus has variable hypopigmentation Associated systemic syndromes with albinism are Chediak -higashi syndrome Mild oculocutaneous albinism Leukocytic abnormalities Prognosis for life is poor death in the 2nd decade Hermansky -pudlok syndrome Mild oculocutaneous albinism Platelet…
