Neutrophils are the first and most numerous cells arrive at the site of inflammatory insult and among first to die, alfa defensin released from apoptotic neutrophils and augment the antimicrobial properties of macrophages. Defensin are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in granules of neutrophils and paneth's cell of the intestine and called alfa defensin, also found in epithelia of mucosal surfaces of the intestine, respiratory tract, urinary tract, vagina known as beta-defensin.
Defensin alfa 1to4 plays a role of phagocytic mediated host defense. COVID 19 infection affects 30% sicker patients by formation of small and big clots that create a lethal blockage in the patient's lungs, kidney heart and brain. Alfa defensin speeds up the creation and formation of blood clots and prevents their disintegration, its found…
