Amiodarone HCl is a member of a class of antiarrhythmic drugs with predominantly Class III effects. Almost three-fourth of patients receiving chronic amiodarone therapy experience side effect, however it is still considered as life saving antiarrhythmic agent. Here we share general information about amiodarone. Amiodarone, an iodinated benzofuran derivative that is widely used for the treatment of cardiac arrhythmia. It is a potent antiarrhythmic class III agent which also has class I, II, IV actions.
It is a ‘broad-spectrum’ in its action and effectiveness. Dosage Adult dose for arrhythmias Tablets: 100 mg, 200 mg, 300 mg and 400 mg Intravenous injections: Initial intravenous dose, 1000 mg over the first 24 hours of therapy. (For first 10 min-150 mg i.e 15mg/min followed by 360 mg over the next 6 hours (1 mg/min). Maintenance infusion: 540 mg over the remaining 18 hours (0.5…
