Antacids are salts of aluminium and magnesium, which are having property to buffer and neutralizing gastric acid present in the stomach,.antacids have served us well for over a century. Recent endoscopic studies confirmed the efficacy of antacids in the healing of duodenal ulcer but efficacy doubtful in the case of gastric ulcer and controversial in the case of ulcer dyspepsia and NSAID-related ulcers. Indication of antacids are: Gastroesophageal reflux disorder Pregnancy-related reflux Prophylactic administration found useful in reducing bleeding from stress ulcers and erosive hemorrhagic gastritis in critically ill patients.
Types of antacids: Aluminium hydroxide having significant and prolong neutralizing effect but can constipation and depletion of phosphorus. Magnesium hydroxide fast and short acting but can causes diarrhoea A combination of both Al and Mg is more useful because…
