Myasthenia gravis is a rare autoimmune neuromuscular disease caused by the production of autoantibodies against nicotinic acetylcholine (Ach) receptors present at the neuromuscular junction. These autoantibodies can reduce the efficacy of synaptic transmission in two ways: By reducing the number of functional receptors. By interfering with Ach to bind to its receptors. This leads to decreased communication between motor neurons and the skeletal muscle that mostly affects the cranial muscles such as eyelids, eye muscles, oropharyngeal muscles and limb muscles.
One of the primary symptoms of myasthenia gravis is drooping eyelids and choking on food. Tensilon (edrophonium chloride) test is used to diagnose myasthenia gravis. ##Disclaimer## The content provided on Docplexus is intended for educational purposes only. While we strive to ensure its accuracy, we make no warranties, explicit or…
