Ceftazidime-avibactam is a combination of a cephalosporin and a beta-lactamase inhibitor used in complicated intra-abdominal infections (cIAI). It is used in combination with metronidazole to treat cIAI. Urinary tract infections are also treated by this antibiotic combination. This article will focus on primary information of this combination drug.
Ceftazidime-avibactam is also indicated for the treatment of complicated urinary tract infections (cUTI) including pyelonephritis. It is a third generation antibiotic to treat the following bacteria that are mostly Gram-negative. Escherichia coli, Klebsiella pneumoniae Proteus mirabilis Providencia stuartii Enterobacter cloacae Klebsiella oxytoca Pseudomonas aeruginosa Citrobacter koseri Enterobacter aerogenes Citrobacter freundii Proteus spp Mechanism of Action The ceftazidime component of the drug is a cephalosporin antibacterial molecule…
