Clinical signs of jaundice are generally observed when serum bilirubin levels exceed 2.5 to 3.0 mg/dL. Given the nonspecificity of this finding, it can represent other disorders too such as bilirubin metabolism defects, hepatocellular dysfunction, or biliary obstruction. Evaluation of the elevated levels of alkaline phosphatase in cholestasis helps to differentiate between these disorders. The utilization of a standardized approach for patients with hyperbilirubinemia will lessen unnecessary testing and also improve patient outcomes.
As clinical signs like yellowing of eyes or skin can be nonspecific for identifying the underlying cause of the disease, a stepwise approach to evaluation is essential for accurate diagnosis and an effective treatment plan. To learn more about “ Approach to Jaundice ”, join an exclusive session with Dr. K V Giriraja on 18 th May 2022, 3.00 PM IST…
