A very less concentration of the drug reaches aqueous humor after topical instillation due to lacrimal drainage. Ophthalmic nanoemulsions enhance drug penetration through corneal tight junctions and form a thicker lipid layer, thereby improving bioavailability.
Lipid-containing eye drops reduce the symptoms of dry eye disease (DED) and preserve tear film quality when used before adverse environmental exposure. This article provides an in-depth understanding of lipid-based nanosystems and their advantages over non-lipid-based artificial tears.
