Opsoclonus Myoclonus Syndrome (OMS) is a rare neurological condition associated with neuroblastoma in the majority of all childhood cases. The reason for the association of neuroblastoma in OMS patients is still unknown. In this study, genomic copy number profiles of the tumors of patients with neuroblastoma and OMS were analyzed to identify specific genetic alterations associated with the disease. What is Opsoclonus Myoclonus Syndrome?

Opsoclonus Myoclonus Syndrome often called “dancing-eyed syndrome,” is a rare neurological condition defined by rapid, multidirectional, conjugate eye movements and sudden, quick jerks of a muscle affecting the trunk, face, and extremities. These symptoms are often accompanied by behavior and personality changes in children, like irritability and sleeping disturbance, and developmental regression. When occurring in children, OMS is associated with…