India has the highest burden of tuberculosis in world with over 2.5 million people living with TB every year. As per WHO global TB report 2015, for the year 2014,deaths due to TB were estimated in india to be 222000 which is higher than other country. World Health Organization estimates that upto 1/2 million new cases of multi drug resistant cases occur every year.Multidrug resistant TB is defined as a form of TB resistant to first line treatment drugs as rifampicin and isoniazid,5% of all cases of TB around the globe estimated as mdr tb ,3.5% newly diagnosed and 20% from previously treated patients.

The main causes of MDRTB either because of inappropriate drug treament or irruglarly taken drugs or defaulter patients. This is treated by second line of drugs or dotplus for 6 months to 18 to 24 months. Extensively drug resistant TB when bacteria become resistant to one drug from each…