Blinding refers to the concealment of group allocation from one or more individuals involved in a clinical research study. The French Academy of Sciences originated the first recorded blind experiments in 1784: the Academy set up a commission to investigate the claims of animal magnetism proposed by Franz Mesmer. Reason for blinding a study: Blind testing is used wherever items are to be compared without influences from testers' preferences or expectations, for example in clinical trials to evaluate the effectiveness of medicinal drugs and procedures without placebo effect, nocebo effect, observer bias, or conscious deception.
Types of Blinding: In a single-blind experiment, the individual subjects do not know whether they are so-called "test" subjects or members of an "experimental control" group. Single-blind experimental design is used where the experimenters either must know the…