35-year-old Adam is brought to the emergency department by an ambulance after being involved in a motor vehicle crash. Upon examination, you notice that he is significantly bleeding from his thigh, so you decide to give him a blood transfusion. Five minutes later, he develops shortness of breath, one episode of non-bloody vomiting, and a diffuse rash with erythematous borders that starts to appear all over his body. Also, his blood pressure drops to 60 over 40 millimeters of mercury.
Some days later, you see 50-year-old Jack, who’s complaining of fever, malaise, and a decreased production of urine for the past two days. On further questioning, Jack tells you that he underwent a kidney transplant one month ago. Upon examination, you realize that he has a high blood pressure of 150 over 80 millimeters of mercury. You decide to perform a biopsy of his transplanted kidney, which reveals a…
