Crystalloid solutions (generally isotonic saline) are typically used in liquid resuscitation involving non-trauma patients in ICU. Whether buffered crystalloids such as lactated-Ringers solution can be used instead of isotonic saline is not known. A new study suggests that buffered crystalloids do not reduce the rate of acute kidney injury (AKI). Saline (0.9% Sodium chloride) is the most common fluid administered intravenously. However, in some cases, it has found to be associated with AKI with increased mortality.

In critically ill patients for liquid resuscitation, isotonic saline is most commonly used. The use of other buffered crystalloids such as lactated-Ringers solution has not been established. The scientists from New Zealand assessed whether buffered crystalloid solutions can be effectively used in critically ill patients for liquid resuscitation. They assessed if buffered…