Dopamine functions in the brain as a neurotransmitter. However, the latest findings have suggested a significant role of dopamine in controlling the immune defense mechanism of the body. This article is aimed to discuss the key findings of the research and the mechanism of dopamine induced immune response. Immune reactions are essentials part of host defense mechanism.
Humoral immunity is a major component the immune system that protects the host from invading pathogen and toxins by virtue of neutralizing antibodies. A typical humoral response necessitates antigen presentation followed by cytokine induced maturation and proliferation of B cells to antibody secreting plasma cells. The process requires the formation of immunological synapse where Major Histocompatibility Complex (MHC) containing pathogen/ toxin antigen fragment interacts with receptors on T cell. Germinal centers are…