The urea cycle helps to eliminate the excess nitrogen and nitrogenous metabolic compounds produced from protein metabolism. It involves five catalytic enzymes, one cofactor-producing enzyme, and two amino acid transporters. A deficiency of any of these components results in a urea cycle disorder (UCD).
In recent times, liver transplantation via advanced methods is gaining popularity for treating metabolic pathology and the neurocognitive deficits associated with UCDs. Source: NCBI-Stat Pearls Click to answer!
