Carcinoma cuniculatum is a rare variant of squamous cell carcinoma characterized by its distinctive endophytic growth pattern resembling rabbit burrows, posing a significant diagnostic challenge for clinicians. Often mistaken for benign conditions such as chronic warts, plantar ulcers, or other hyperkeratotic lesions, its insidious progression and subtle clinical presentation can delay accurate diagnosis and appropriate treatment. Histopathological examination is critical, revealing keratin-filled crypts and minimal cytological atypia despite its aggressive local invasion.
The condition underscores the importance of maintaining a high index of suspicion for malignancy in chronic, non-healing lesions, especially in high-pressure areas like the soles. To gain detailed insights into carcinoma cuniculatam, join proficient Head and Neck Oncosurgeon Dr. Shivam Pandya on 19 th June 2025, at…