The pathogenesis of osteoporosis has its roots in the impairment of the bone formation process, that is known as Bone Remodeling. This article deals with the mechanism of bone formation and the clinical presentation of osteoporosis. It points out the risk factors associated with osteoporosis and related clinical conditions. Bone Formation and osteoporosis: The bone formation is a complex and continuous process, also known as Bone Remodeling .
It involves two types of bone tissues, osteoblasts, and osteoclasts that work distinctly and serve different functions. Osteoclasts are macrophages that serve the function of bone destruction ( bone resorption ) and, osteoblasts are the connective tissues that function in a bone matrix formation. Cells that are involved in a bone remodeling process strengthen the bones by providing minerals such as calcium, phosphorus, magnesium and also increase…
