Affecting up to 2% of the population worldwide, vitiligo poses significant undesirable aesthetic effects on face and limbs. The two ways of vitiligo managements are repigmentation and depigmentation. This article discusses consideration factors in depigmentation therapy with Monobenzone in extensive vitiligo management. Vitiligo is a chronic and progressive disorder caused by autoimmune destruction of melanocytes.

The condition is characterized by the appearance of one or more well-circumscribed, hypopigmented, white macules or patches. The problem with vitiligo is multifaceted: The negative aesthetic effect (especially in population with dark skin) results in significant psychological effect such as depression In some cultures, poor knowledge regarding vitiligo leads to the abrupt imagination of the etiology of the disease, such as STD making vitiligo a social stigma. Repigmentation vs…