Cutaneous T-cell lymphoma (CTCL), especially its mycosis fungoides variant, poses a significant diagnostic challenge due to its mimicry of chronic dermatitis and other inflammatory dermatoses. Early stages often show nonspecific histology and can lead to years of misdiagnosis. Immunophenotyping and T-cell receptor gene rearrangement testing have improved diagnostic precision. Clinical suspicion is crucial, especially in persistent, pruritic, and treatment-resistant patches.
Recognizing classic signs like poikiloderma, palmoplantar involvement, and progression to plaques is essential for early diagnosis. Let’s test your CTCL expertise. (Scroll down to answer the question) ##References## Clinics in Laboratory Medicine, Journal of Cutaneous Pathology, and The Journal of Clinical and Aesthetic Dermatolog## ##Disclaimer## The content provided on Docplexus is intended for educational purposes…
