A 62 years old patient of Hypertension and mild DM, on Enalapril 10mg + HCZ, Metformin, for twenty years. Two days ago, he feels that he had a sting of insect in the night on palm, after nodules appeared over creases and very painful to touch.

What is this phenomenon 1- insect bite allergy 2- contact dermatitis 3- Infection in the crease?