Changes in lifestyle and environmental conditions have led to an increase in the incidences of genetic diseases, including severe neurological conditions. Identifying the genetic factors underlying neurological conditions is often crucial for their management. The lack of awareness about genetic diagnostic modalities poses a challenge for genetic screening. One of the most crucial yet lesser-known modalities is next-generation sequencing (NGS).
This article outlines the role of NGS in the diagnosis of neurodegenerative diseases. Next-generation sequencing and its role NGSis a complex sequencing method that reads millions of nucleotide sequences in a DNA sample within a short time frame. The data obtained from NGS can accurately indicate discrepancies in genetic sequences, thus enabling a root cause analysis. This data can be used to offer personalized medicine and treatments that can…
