Standard drug therapy for hepatitis C has undergone significant changes in the recent decade. The shift has been towards safer and more effective therapies focused on achieving cure. Hepatitis C is a global health care problem as chronic infection occurs in a significant majority (60% to 85%) of those infected. Chronic hepatitis C is associated with progressive liver failure, cirrhosis and hepatocellular carcinoma. In India the burden of HCV is compounded by the lack of accessibility and affordability of treatment and the spread of the infection via unsafe healthcare practices.

Hepatitis C treatment goals include Achieving a sustained virologic response(SVR). Limiting the sequelae of cirrhosis and decompensation of liver disease. Reducing the risk of hepatocellular carcinoma. A sustained viral response (SVR) is aviremia 24 weeks after completion of therapy. This is defined by the…