Effect Of Bedaquiline On Mortality Of Patients With Drug-Resistant TB

Synopsis A recent clinical study demonstrates that treatment with Bedaquiline is associated with a 3 times reduction in mortality for patients with multidrug-resistant or rifampicin-resistant tuberculosis and an even larger reduction in mortality for patients with extensively drug-resistant tuberculosis. This week's ' MED FACT ' discusses a clinical trial from The Lancet Respiratory Medicine , “ Effect of Bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study ”. July 2018.

Authors : Schnippel K; Ndjeka N; Maartens G; Meintjes G; Master I; Ismail N; Hughes J; Ferreira H; Padanilam X; Romero R; te Riele J. Key Takeaways Bedaquiline-based treatment regimens is associated with a large reduction in mortality of patients with drug-resistant tuberculosis. Objective Study Type Participants To compare the mortality between patients who…