Synopsis   A  clinical study demonstrates a significant improvement in the adipokine profile in prepubertal obese children with weight loss after 1-year lifestyle intervention. This week's ' MED FACT ' discusses a clinical trial from Endocrine Research, “ The effect of weight loss on body composition, serum bone markers, and adipokines in prepubertal obese children after 1-year intervention ”. Dec 2017. Authors : Gajewska J; Ambroszkiewicz J; Klemarczyk W; Chełchowska M; Weker H; Szamotulska K.

Key Takeaways A positive relationship exists between fat and bone mass in prepubertal children. Objective Study Type Participants To analyse the effect of weight loss on bone markers and adipokines in prepubertal obese children 1-year intervention program   40 What Was The Need For This Study? It has been recognized that the adipocyte-derived hormones, leptin and adiponectin, could modulate bone…