Euglycemic diabetic ketoacidosis (EDKA) represents a critical but often underrecognized complication of diabetes in pregnancy, defined by significant ketoacidosis with normal or only mildly elevated blood glucose levels (<200 mg/dL). Pregnancy-specific physiological changes—such as increased insulin resistance, enhanced lipolysis, and a predisposition to accelerated starvation —significantly increase susceptibility to EDKA , with reports indicating that nearly one-third of DKA cases in pregnancy may present with euglycemia .
The article underscores key diagnostic challenges, where reliance on glucose levels alone may delay diagnosis, and reinforces management priorities including early recognition, prompt intravenous fluid resuscitation with dextrose-containing solutions, continuous intravenous insulin to suppress ketogenesis, and careful correction of electrolyte disturbances. Timely…
