CHD is the leading cause of perinatal and infant death from a congenital birth defect. Critical CHD accounts for approximately 25 percent of all CHD. In infants with critical CHD, the risk of morbidity and mortality increases when there is a delay in diagnosis and timely referral to a tertiary center with expertise in treating these patients. To identify the potential risk of CHD following few factors must be evaluated: Pre-term birth: Risk is 2-3-fold higher in preterm (gestational age <37 weeks) compared with term infants.

Family history: Again, the risk is 3-fold higher with family history. Genetic syndromes : A study suggest 7% cases of all CHD patients. Maternal factors: Maternal diseases like diabetes mellitus, hypertension, obesity, phenylketonuria, thyroid disorders, systemic connective tissue disorders, and epilepsy increase the risk for CHD in newborns. Assisted reproductive…