Transfusion of blood and blood products is one of the most frequently performed procedures during hospitalizations. However, with a growing evidence base supporting the use of restrictive transfusion strategies,  emerged as an evidence-based, multidisciplinary approach to optimizing the care of patients who may need a transfusion. Principles of clinical transfusion practice: The patient with acute blood loss should receive effective resuscitation  (intravenous replacement fluids, oxygen and other medication) immediately and the need for transfusion is estimated thereafter.

The patient’s haemoglobin (Hb) value, although important, should not be the sole deciding factor in the decision to transfuse blood. This decision should be supported by the need to relieve clinical signs and symptoms and to prevent significant morbidity or mortality. …