Researchers from Baylor School of Medicine have identified a viral protein known as M pro that is critical for viral replication of the SARS-CoV-2. Using DEC-Tec, a DNA-encoded chemistry technology, billions of chemicals were screened against M pro . Importance of M pro as a therapeutic target for SARS-CoV-2 M pro , a primary protease of SARS-CoV-2, is a critical component of the lifecycle of coronaviruses and a therapeutic target that is independent of the current vaccination methods.
Viruses like SARS-CoV-2 must replicate inside human cells; therefore, identifying chemicals that can block the important aspects of this process is critical to prevent the virus from propagating. The uniqueness of the new screening process High-throughput screening (HTS) , the most commonly used method for identifying medicines, involves screening of up to one million compounds in the individual test…
