Ferumoxytol, an iron oxide nanoparticle, is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. It is a form of iron that must be given by injection. You may need extra iron because of blood loss during kidney dialysis treatment. Ferumoxytol has an “off label” usage for clinical pediatric cardiac and vascular imaging also. Even for it label use, it has an FDA black box warning for severe hypersensitivity/anaphylaxis.
How safe will it be for its “off-label” use in pediatric patients? A study published in the journal called Investigative Radiology in March 2016 issue elaborated the safety of “off-label” use of ferumoxytol. The aim of this study was to assess the safety profile of ferumoxytol as an intravenous magnetic resonance imaging contrast agent in children. Design of the study In this study, the safety of ferumoxytol administrations as an "off-label"…
