A case report in BMC Ophthalmology (2025) describes a rare instance of ocular frostbite following a 3-hour marathon in subzero temperatures (−16 °C to −23 °C) . The patient presented with blurred vision, photophobia, and eye irritation, with examination showing stromal and endothelial corneal edema, bilateral epithelial defects, and conjunctival congestion . After four weeks of topical therapy , visual acuity and epithelial integrity were restored, though a permanent endothelial scar persisted. The report highlights that ice crystal formation can directly injure both the epithelial and endothelial layers of the cornea, underscoring the need for prompt recognition and protection in extreme cold environments.
To read more ; Click here ##Reference## Yin, Y., Gong, L. The ocular frostbite involving cornea caused by low-temperature environment. BMC Ophthalmol 25, 542 (2025).##
