An Identification of a genetic variant which regulates a gene has been done for determining bone density and fracture risk. Researchers from Harvard-affiliated Hebrew SeniorLife Institute for Aging Research (IFAR), in collaboration with scientists from a number of international institutes, have identified a genetic variant regulating a gene responsible for bone mineral density and fracture risk. Findings from this study--funded in part by grants from the National Institutes of Health (NIH)--are published in the journal Nature and could lead to interventions that may prevent fractures in older adults.
Osteoporosis, a word meaning "porous bone," is a disease that weakens bones, making them brittle and susceptible to fracture. According to the NIH, an estimated 53 million Americans have osteoporosis or are at risk of developing the disease due to low bone mass. Previous research has found…