Patients on peritoneal dialysis are at higher risk of developing infectious complications (exit-site, tunnel infections and peritonitis). Infection related hospitalisations are associated with readmission and significant mortality. In this regard, age and diabetes mellitus are non-modifiable risk factors; whereas, obesity, smoking and patient training are some of the modifiable risk factors. This article reviews the efficacy of topical mupirocin and gentamicin in preventing peritoneal dialysis related infections.
Generally gram-negative infections result from touch contamination and sometimes from a bowel source such as constipation, colitis, or transmural migration. Gram-positive bacteria infections are due to hospitalisation, catheter loss, and failure of peritoneal dialysis. The international guidelines recommend on using topical exit site or nasal antibiotics to reduce the…
