Microbes present in the gut are known to be responsible for maintenance of overall health of an individual. Recent reports are suggesting an exciting possibility of bone health getting affected by gut microbes. The current article discusses the evidence and mechanisms of this gut-bone axis. The human microbiota refers to the collective microbial species present on or inside the human body. Gut microflora or intestinal microbiota is the community of microorganisms that reside inside the digestive tract, mainly intestine.
It comprises of about 10 14 microbes and about >10 3 different species. Majority of these species are anaerobic and non-pathogenic. The normal gut flora helps in digestion, synthesizes certain vitamins (B and K), and prevents colonization of other microbes. It also plays an important role in maintaining the immune system. Due to the close interaction between immune and…