A study conducted on pregnant women to check the effects of infections on the neurodevelopment of the fetus. The study tested the ToRCH agents which may be responsible for spontaneous abortion, intrauterine growth restriction, preterm labor etc. This article provides highlights of the study and a possible link between HSV-2 infection and risk of developing autism, especially in a male child. Study Background Autism spectrum disorder (ASDs) includes various neurodevelopmental syndromes with respect to social impairment, the deficit in language and communication including behavioral issues.

There is no definitive biomarkers and pathogenesis in most instances are unexplained for ASD. Hence largely the diagnosis relies on the clinical criteria. Infections during pregnancy are suggested as a risk factor in several neurodevelopmental disorders, including ASD. It is observed in the animal…