Inflammatory bowel disease (IBD) is a chronic disease of the GI tract attributed to the aberrant activity of the immune system. Increasing evidence suggests that patients with IBD are at an increased risk of inflammatory skin diseases (ISDs). The 2 principal forms of IBD are: Crohn’s disease (CD): affecting any part of the gastrointestinal tract Ulcerative colitis (UC): affecting the colon and rectum The pathophysiology of the condition is not well understood, however, the interplay between a genetic predisposition to disease susceptibility and many exogenous factors alter immune function, triggering chronic intestinal inflammation are thought to play the role.
Several studies have established the association of IBD with various inflammatory skin diseases (ISDs) including psoriasis, rosacea, and atopic dermatitis (AD). The overlaps in the immunologic characteristics probably trigger…
